In a recent study, the contribution of soy and other bioactives in reducing cardiovascular disease risk in plant-based diet are investigated. Cardiovascular (CV) disease is the leading cause of mortality in most Western countries.? Despite there being a tremendous amount of research on risk factors of CV disease, the general population continues to misinterpret risk factors and lacks the knowledge of how to make lifestyle changes.? Using available epidemiology and clinical data from around the world, researchers investigated the role of food and plant components on human vascular health.? The compiled data indicates consumption of green tea extract, red yeast rice, coenzyme Q10, soy, omega-3 polyunsaturated fatty acids, curcumin, and vitamin E, prevents vascular aging. This is observed through less hardening or stiffening of the arterial walls, which improves function for those who consume these plant-based bioactives as part of a balanced diet. These foods contain bioactives that have short-term lipid-lowering effects in addition to reducing lipid oxidation which has been linked to hardening of the arteries, thus decreasing the risk of cardiovascular mortality. This research further supports that soy foods can play an active role in reducing the risk of cardiovascular disease and vascular aging.